Conquer Eczema with Ceramide-dominant Ceradan® for Optimal Skin Barrier Restoration
2 mins read
With the buzz around ceramides, they may seem like the latest skin health trend that will rise and fade fast, but the science behind their skin care applications clearly shows why this wonder ingredient is here to stay. It’s all about optimal skin restoration through barrier repair—a long-term solution based on the natural composition of skin.
But first, what are ceramides?
They are intercellular lipids1 on the outermost layer of the skin; an essential part of the barrier that seals in moisture and protects against irritants, allergens, bacteria, and viruses.
Often referred to as the glue or mortar that holds skin cell “bricks” together, they’re actually more fun to visualise as a layer of jelly glaze keeping fruit neatly arranged on a tart!
Why are ceramides used for eczema treatment?
In eczema-prone skin, this natural barrier and its functions are disrupted by ceramide deficiency (up to 30-50% less vs. normal skin levels). This decrease in ceramides leads to skin dryness and sensitivity, which in turn help bring about inflammation and that dreaded itch.
So, do ceramides work for eczema-prone skin?
81.3% of the participants in the study (Singaporean children under 6) who initially marked their status as being “quite unhappy” (3 on a scale of 5) with their eczema severity, showed improvement after 12 weeks of treatment. For almost half the participants (45.5%), an eczema relapse was prevented.
In another study,3 participants (Singaporean children aged 8-16) gave the ceramide-based cream an irritation score that was 48% lower than a urea-based one. This is significant because dealing with eczema flares can be a huge struggle for kids and their parents. Creams that further irritate skin become bane more than boon.
Effective in reducing flares plus low on irritation, optimal ceramide science works according to those who have eczema and it’s clinically proven4 too. Now, experts weigh in on a big question:
Are all ceramide products made equal?
“Ceramides with lipids and cholesterol in the right ratio have been proven to be important in holding skin cells together to build a strong protective barrier against eczema flares. Maintaining this barrier is a critical part of defence,” adds Dr. Joyce Lim, Senior Consultant Dermatologist at Joyce Lim Skin & Laser Clinic and Past Division Head of Dermatologic and Laser Surgery at National Skin Centre.
A key phrase here is “the right ratio.” Many beauty products—face/body moisturisers, serums, and masks, makeup, even shampoo—contain ceramides. But the clinically proven, optimal ceramide science uses the right type of ceramide in a 3:1:1 ratio of ceramide: cholesterol: free fatty acids.
This optimal ratio, similar to what’s found in healthy skin, is the core product principle of Ceradan®, the #1 Top-of-Mind Moisturiser Brand among Singapore dermatologists.*
This optimal ceramide science can be found across the formulations of its extensive line of skin care products. Long-term eczema treatment via skin restoration—in lieu of recurring (and frustrating), short-term eczema flare management—is within reach with Ceradan® products and solutions available in these categories: cleansing, intensive treatment, and moisturisation. Ceradan® also has a range of child essentials.
*IQVIA HCP Recommendation Tracking for Moisturiser 2018, private dermatologists
Results may vary.
- Choi, Myeong Jun, and Howard I Maibach. “Role of ceramides in barrier function of healthy and diseased skin.” American journal of clinical dermatology vol. 6,4 (2005): 215-23. doi:10.2165/00128071-200506040-00002
- Koh, Mark Jean-Ann et al. “Comparison of the Simple Patient-Centric Atopic Dermatitis Scoring System PEST with SCORAD in Young Children Using a Ceramide Dominant Therapeutic Moisturizer.” Dermatology and therapy vol. 7,3 (2017): 383-393. doi:10.1007/s13555-017-0186-1
- Ho, Valerie Pui Yoong et al. “Comparing the Potential for Irritation of a Ceramide-Based Moisturizer with a Urea-Based Moisturizer for Pediatric Atopic Dermatitis.” Dermatology and therapy vol. 10,4 (2020): 807-813. doi:10.1007/s13555-020-00388-6
- Kircik, Leon H et al. “Evaluating Clinical Use of a Ceramide-dominant, Physiologic Lipid-based Topical Emulsion for Atopic Dermatitis.” The Journal of clinical and aesthetic dermatology vol. 4,3 (2011): 34-40.