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Why are Ceradan® products beneficial for eczema-prone skin?

Ceradan® range of products contain a ceramide-dominant lipid-based formulation that addresses two main issues in eczema-prone skin, a condition related to dry and sensitive skin.R1,R2

The symptoms experienced by individuals with eczema-prone skin result from a compromised skin barrier that occurs due to a deficiency of an important lipid structure, ceramide.R3,R4

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Figure 1: When there is a lack of ceramide in the skin, it causes the skin barrier to breakdown.

The mainstay management of symptoms in eczema-prone skin is to ensure that products used for washing/cleansing and moisturising the skin are suitable for the skin type.R5 Emollient-based products are recommended for this as it is able to help replenish and retain moisture.R6

However, it does not address the lack of ceramides.

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Figure 2: Eczema-prone skin has much less lipids in its structure, making it an important issue to address when managing it.

Ceramide-dominant lipid-based formulations on the other hand address ceramide deficiency by essentially replacing the missing ceramides and, restoring and repairing the skin’s natural barrier.R7,R8

Ceramide-dominant lipid-based formulation contains the three lipid components found in the skin. These are ceramide, cholesterol and fatty acids. In healthy skin, ceramide is the most abundant lipid and plays a very important role in supporting the normal skin barrier.R3, R4, R9

The unique science behind our products is that the ceramide-dominant lipid-based formulation used in Ceradan® has a 3:1:1 ratio wherein the concentration of ceramide is three times more than the other lipids. In fact, our products are the only available in the market with this specific type of formulation.

Do you know?
Ceradan® product formulation is the only one with a ceramide: cholesterol: fatty acid ratio of 3:1:1

How does ceramide-dominant lipid-based formulation work?

The process of ceramide-dominant lipid-based formulation work:

  1. The product permeates into the topmost layer of the skin (also known as the stratum corneum)
  2. It becomes incorporated into the skin cells (also known as keratinocytes)
  3. The ceramide is then secreted back into the stratum corneum.

The ceramide in the formulation essentially replaces missing ceramides by becoming incorporated into the natural process of ceramide secretion.R8

By doing so, these formulations reduce inflammation in eczema-prone skin and restore the normal skin barrier.

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Figure 3: Ceramide-dominant lipid-based products penetrate the skin. The ceramide is incorporated into the skin cells and secreted back into the skin layer to restore and repair the skin’s barrier. Ceradan® range of products contain 3 times more ceramide compared to cholesterol and fatty acids and is the only marketed product with this specific formulation.

What is special about Ceradan® 3:1:1 ratio?

Ceradan® range of products does not only carry the ceramide-dominant lipid-based formulation.

Its unique 3:1:1 ratio of ceramide:cholesterol:fatty acid is similar to that found in healthy skin. This specific ratio has been tested and shown to exert optimal benefits supporting accelerated optimal skin barrier repair.R10-R12

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Figure 4: A clinical study showed that the ratio of ceramide:cholesterol:fatty acid of 3:1:1 lends to accelerated optimal skin barrier repair and increases moisture in the skin. Adapted from Man M-Q et al. 1996

Its unique 3:1:1 ceramide-dominant lipid-based formulation repairs the compromised skin barrier by incorporating ceramide into skin cells, creating an accelerated restoration of a healthier skin barrier.

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Figure 5: Effect of Ceradan® unique 3:1:1 ratio that helps in the accelerated repair of the skin barrier

Ceradan® range of products has been clinically tested and shown to prevent 1 out of 2 symptom recurrence in children with eczema-prone skin conditions.R13

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Figure 6: 1 in 2 children using Ceradan® products experience no recurrence of symptoms. Adapted from Koh M-J et al. 2017

While 9 in 10 users were satisfied with the regimen of washing and moisturising with Ceradan® products.R13

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Figure 7: Almost 9 in 10 patients with eczema-prone skin indicated that they would repeat the regimen of bathing and moisturising with Ceradan® products. Koh M-J et al. 2017

Soothing gel can help calm the skin.

Lennix is super sensitive to mosquito bites not only does it swells up to the size of golf balls but when he scratches it ….
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Joanne

Singapore

Ceradan Hydra moisturiser is able to maintain the hydrated.

Having eczema since I was 2 weeks old at birth, I’ve been on the search for products to keep the eczema under control ….
Read More

Cheryl

Singapore

It’s soap free and safe for all skin types

Honestly though, this 3 are my most used products from @ceradan311sg ? I love using the wash on Shayera & Zayne as ….
Read More

Jane

Singapore

It’s a very gentle and baby-safe product.

We were introduced to Ceradan Skin Barrier Repair Cream by Marc’s paediatric when he started to develop a neck rash from all the sweating, milk and drool ….
Read More

Cheryl

Singapore

It is hypoallergenic and 100% safe for newborn.

My baby is almost 2 months old, for the past weeks, I’ve been overwhelmed by frequent diaper changing and feeding my baby day and night ….
Read More

Adeline

Singapore

Ceramoz will make your life better!

Recommended by a pediatric dermatologist, my 4 YO girl has been using the Ceramoz for more than 2 years now. It is truly the best of both worlds ….
Read More

Alfred

Singapore
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  • Lennix is super sensitive to mosquito bites not only does it swells up to the size of golf balls but when he scratches it he gets a bacterial skin infection which either lands him in hospital for IV antibiotics or heavy doses of oral antibiotics.

    So now whenever he gets bitten we immediately apply antiseptic solution and then put a bandaid on it so he wouldn’t be able to scratch.

    However the area around the bite becomes very dry and scabby possibly due to lack of air because we leave the bandaid on until the bite heals? We have been using @ceradan311sg soothing gel to help calm the skin so scratching is minimised to prevent further damage and it’s been working great! We ❤️ it!

  • Having eczema since I was 2 weeks old at birth, I’ve been on the search for products to keep the eczema under control. One thing I found useful before attending this session is that I “drink” moisturisers by the bottle and only came to know Ceradan since Marc was born. What I didn’t know was Ceradan is great for all ages, all skin types, especially dry, sensitive and eczema ones.

    The texture of the Ceradan Hydra moisturiser is very light yet is able to maintain the hydrated feeling for quite a while. And understanding from Dr Lynn that the key issue with eczema skin is to build up the skin’s barrier to minimise inflammation and infection, using a moisturiser with 3:1:1 ceramide dominant ratio is essential.

  • Honestly though, this 3 are my most used products from @ceradan311sg ? I love using the wash on Shayera & Zayne as it puts my mind at ease knowing that it’s soap free and safe for all skin types. As for the diaper cream, I use it on the kids even when there’s no rash to ensure that they’re protected. I used it on myself the other day when I had a minor rash on my hand and it helped! As for Ceramoz, it’s part mosquito repellent and part moisturiser! It’s the kiddos must have when they go over to my in-laws place which is a landed space, so you know how mosquitos love to party inside.?

  • We were introduced to Ceradan Skin Barrier Repair Cream by Marc’s paediatric when he started to develop a neck rash from all the sweating, milk and drool in between his neck folds. And later, when Marc started on his helmet therapy, the orthopaedic suggested using Ceradan Body Wash to help minimise any possibility of heat rashes and keep his skin moisturised.

    Having used Ceradan products on Marc for quite a while now, we do find that it’s a very gentle and baby-safe product. Upon using the Ceradan Skin Barrier Repair Cream, his neck rash was under control very quickly and it’s been very effective even for myself when I have eczema flare ups. Ceradan Regimen, which consists of Ceradan Skin Barrier Repair Cream and Ceradan Body Wash, is suitable for children as young as newborns and it has demonstrated clinically-proven efficacy in a study conducted by KK Women’s and Children’s Hospital and National Skin Centre in Singapore to prevent 1 in 2 eczema flares in Singapore children.

    Since Marc loves swimming, and the chlorine in the water is very drying for the skin, I highly recommend Ceradan Body Wash to cleanse and maintain his gentle baby skin as hydrated as possible.

  • My baby is almost 2 months old, for the past weeks, I’ve been overwhelmed by frequent diaper changing and feeding my baby day and night. ?‍♀️?? Diaper rash is also every mum’s nightmare so choosing the right diaper cream is so important. Ceradan’s diaper cream is clinically proven and also recommended by KK Children & Women’s Hospital.

    It is hypoallergenic and 100% safe for newborn.

    I’m thankful to be able to try out this diaper cream for my baby with its unique triple protective actions◾Zinc oxide to seal out wetness ◾Octenidine to control yeast overgrowth ◾Contains 3:1:1 ratio of ceramic, cholesterol and free fatty acids to repair skin barrier.

    Thanks for keeping my baby’s skin rash-free!

    Ceradan is available at Watsons, Guardian and Unity stores.

  • Recommended by a pediatric dermatologist, my 4 YO girl has been using the Ceramoz for more than 2 years now. It is truly the best of both worlds, being able to moisturise and protect against mosquito bites at the same time!

    One big problem we had to deal with when my girl started childcare was mosquitoes ?. Doesn’t help when she had eczema and very sensitive skin. One bite on her and the bitten site would swell and become inflamed. Mosquito patches don’t work at all, and kid-friendly insect repellents either don’t work so well, or are too “spicy” – imagine the whines when she accidentally rubs her eyes after applying the repellent. When we were initially introduced to Ceramoz, we were a bit doubtful but later glad to learn that my girl don’t get bitten by mosquitoes that often anymore! (Truth he told, she only gets bitten when she forgets to apply it after her shower in childcare). It has proved its use so much that I use it now even during her non school days, 2+ years and counting!

    If you have a school-going child with eczema conditions, delicate skin, or is simply a mosquito magnet, Ceramoz will make your life better!

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